Search on: RECEPTOR, EPIDERMAL GROWTH FACTOR 
Descriptors Found: 1
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 1 / 1 DeCS     
Descriptor English:   Receptor, Epidermal Growth Factor 
Descriptor Spanish:   Receptor del Factor de Crecimiento Epidérmico 
Descriptor Portuguese:   Receptor do Fator de Crescimento Epidérmico 
Synonyms English:   Epidermal Growth Factor Receptor Kinase
Proto-oncogene c-ErbB-1 Protein
Receptor Tyrosine-protein Kinase erbB-1
Receptor, ErbB-1
Epidermal Growth Factor Receptor Protein Tyrosine Kinase
ErbB-1 Receptor
Proto oncogene c ErbB 1 Protein
Proto-Oncogene Protein, erbB-1
Receptor Tyrosine protein Kinase erbB 1
Receptor, ErbB 1
Receptor, TGF alpha
Receptor, Transforming Growth Factor alpha
c erbB 1 Protein
c-ErbB-1 Protein, Proto-oncogene
erbB 1 Proto Oncogene Protein
c-erbB-1 Protein
EGF Receptor
Epidermal Growth Factor Receptor
Receptor, Transforming-Growth Factor alpha
Urogastrone Receptor
Receptor, TGF-alpha
Receptor, Urogastrone
Transforming Growth Factor alpha Receptor
TGF-alpha Receptor
erbB-1 Proto-Oncogene Protein
Epidermal Growth Factor Receptor Protein-Tyrosine Kinase
Receptor, EGF  
Tree Number:   D08.811.913.696.620.682.725.400.009.300
D12.776.543.750.630.009.300
D12.776.543.750.750.360.300
D12.776.543.750.750.400.074.300
Definition English:   A cell surface receptor involved in regulation of cell growth and differentiation. It is specific for EPIDERMAL GROWTH FACTOR and EGF-related peptides including TRANSFORMING GROWTH FACTOR ALPHA; AMPHIREGULIN; and HEPARIN-BINDING EGF-LIKE GROWTH FACTOR. The binding of ligand to the receptor causes activation of its intrinsic tyrosine kinase activity and rapid internalization of the receptor-ligand complex into the cell. 
See Related English:   Cetuximab
Genes, erbB-1
 
History Note English:   2000(1987); for EPIDERMAL GROWTH FACTOR RECEPTOR PROTEIN-TYROSINE KINASE use RECEPTOR, EPIDERMAL GROWTH FACTOR 1994-1999 
Allowable Qualifiers English:  
AD administration & dosage AG agonists
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CH chemistry CL classification
DF deficiency DE drug effects
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PH physiology
RE radiation effects TU therapeutic use
UL ultrastructure  
Record Number:   24479 
Unique Identifier:   D011958 

Occurrence in VHL:
 

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